[ANSWERED] An 83-year-old resident of a skilled nursing facility presents to the emergency department with generalized edema of extremities and abdomen.

Discussion: Alterations in Cellular Processes

At its core, pathology is the study of disease. Diseases occur for many reasons. But some, such as cystic fibrosis and Parkinson’s Disease, occur because of alterations that prevent cells from functioning normally.

Understanding of signals and symptoms of alterations in cellular processes is a critical step in diagnosis and treatment of many diseases. For the Advanced Practice Registered Nurse (APRN), this understanding can also help educate patients and guide them through their treatment plans.

For this Discussion, you examine a case study and explain the disease that is suggested. You examine the symptoms reported and explain the cells that are involved and potential alterations and impacts.

To prepare:

  • By Day 1 of this week, you will be assigned to a specific scenario for this Discussion. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

Scenario: An 83-year-old resident of a skilled nursing facility presents to the emergency department with generalized edema of extremities and abdomen. History obtained from staff reveals the patient has history of malabsorption syndrome and difficulty eating due to lack of dentures. The patient has been diagnosed with protein malnutrition

By Day 3 of Week 1

Post an explanation of the disease highlighted in the scenario you were provided. Include the following in your explanation:

  • The role genetics plays in the disease.
  • Why the patient is presenting with the specific symptoms described.
  • The physiologic response to the stimulus presented in the scenario and why you think this response occurred.
  • The cells that are involved in this process.
  • How another characteristic (e.g., gender, genetics) would change your response.

Expert Answer and Explanation

Assessment of Protein Malnutrition Disease

Prior to administering treatment, clinicians have to assess patients, and this assessment is necessary because it informs the caregiver on the best form of intervention for a particular patient scenario. During patient examination, an interventionist assesses the patient’s health background, and clinical manifestations. When working with a patient with a potential protein malnutrition, for example, a caregiver would examine patient factors such as the problem with their denture as well as their age because these are some of the factors that can exacerbate this condition. Thus, this study explores genetics’ role in the development of the protein malnutrition, and determine the reasons for the presenting clinical symptoms.

How Genetics Affect Protein Malnutrition

People’s risk of developing protein malnutrition differs, and genetics plays a role in the causation of this difference. Depending on one’s gene composition, one may prefer certain foods, and dislike others. Different foods provide different nutrients to the body, and when one does not eat foods rich in protein, their risk of developing kwashiorkor increases (Coulthard, 2015). Therefore, genetics causes kwashiorkor by causing an individual to dislike protein-rich foods such as milk.

Reasons for the Patient’s Symptoms

One can attribute the clinical manifestations present in the 83-year patient to the physiological changes linked to the protein malnutrition disease. The patient has a generalized edema of extremities, and this is one of the symptoms associated with the deficiency of the protein, albumen in the body. This protein plays a crucial role in helping hold the blood salts and water, and the lack of this protein may cause water to leak into the fluid tissues. Eventually, this causes the size of the patient’s extremities and abdomen to expand (Mozanzadeh et al, 2018).

Physiological Response to Stimuli

Based on the case study, the 83-year old experiences physiological changes which stem from the lack of the adequate protein in the patient’s body. The edema is one of these responses. The patient has issues with their dentures, and this explains why they experiences difficulty eating. There is a connection between the formation of these dentures and the malnutrition of the protein considering that nutrients play a bigger role in the strengthening of the dentures and the teeth. Based on the patient medical background, they have a mal-absorption syndrome, and this can be a trigger of the protein deficiency (Ellison, 2019).

Cells which are involved in Physiological Response

Cells play significant roles in the absorption of the nutrients and water, and within one’s body, some cells contribute to the formation of the edema. The endothelial cells are responsible for the formation of the edema given their role in the absorption of the salts and water. This is because they help facilitate the exchange of the fluids and salts to and from the blood to the tissues.

Effect of additional Factor

Gender is an additional factor that can alter the pathophysiology of kwashiorkor. Nutrition status may differ across gender, and female seem to be at higher risk of experiencing malnutrition. This is the reason why cases of the kwashiorkor and edema are more prone in women compared to men (Kismul et al., 2014).


In conclusion, edema is a clinical manifestation linked to the malnutrition of the protein, and genetics affects an individual’s risk of developing this malnutrition. This is because the protein controls the absorption of the salts and fluid, and the buildup of this fluid due to the lack of protein may cause the edema to grow. However, gender also plays a role in the development of the kwashiorkor.


Coulthard M. G. (2015). Oedema in kwashiorkor is caused by hypoalbuminaemia. Paediatrics and international child health35(2), 83–89. Doi: https://doi.org/10.1179/2046905514Y.0000000154.

Ellison, D.H. (2019). Clinical Pharmacology in Diuretic Use. Clinical Journal of American Society of Nephrology, 14 (8), 1248-1257. Doi: https://doi.org/10.2215/CJN.09630818.

Kismul, H., Van den Broeck, J., & Lunde, T. M. (2014). Diet and kwashiorkor: a prospective study from rural DR Congo. PeerJ2.Doi:  https://doi.org/10.7717/peerj.350.

Mozanzadeh, M.T.., Yaghoubi, M., Marammazi, J.G., Safari, O., & Gisbert, E. (2018). Effects of Dietary Protein on Essential Amino Acid Deficiencies on Growth, Body Compassion, and Digestive Enzyme Activities of Silvery-Black Porgy (Sparidentex hasta). Int Aquat Res, 10, 45-55. Doi: https://doi.org/10.1007/s40071-017-0187-9.

Place your order now for the similar assignment and get fast, cheap and best quality work written by our expert level  assignment writers.An 83-year-old resident of a skilled nursing facility presents to the emergency department with generalized edema of extremities and abdomen.

Use Coupon Code: NEW30 to Get 30% OFF Your First Order

ANSWERED! 67-year-old female presents with chief complaint

SOLVED! Healthcare continues to be a lucrative target for

SOLVED! Post a brief explanation of the differences between

SOLVED!! Explain how interprofessional collaboration will

SOLVED! Mr. EBR is a 74-year-old retired Hispanic gentleman

[ANSWERED] What parts of the lawmaking process does a nurse have an opportunity to influence the final bill passage?

[ANSWERED] Discuss a formal role where a nurse is in

ANSWERED!! In this assignment you will propose a quality

ANSWERED!! Now imagine that you are a university psychology

ANSWERED! What would spirituality be according to your own

ANSWERED! Based on Case Study: Fetal Abnormality

ANSWERED!! What is your definition of spiritual care?

What our customers say

Essay was good; although need to do few amendments and add few things, overall it was good and justify money paid.


it was good
it has introduction, body paragraphs, and conclusion as well
it was really helpful

Great service. Always provide quick response and best online support and have very very less plagiarism.

Thanks for giving my assignment on time. I really appreciated the work done. This keeps me submitting new assignments.

Thank you my writer. Good job and I really enjoy you fast response. I definitely will recommend to my friends.


Thanks for giving my assignment on time. I really appreciated the work done. This keeps me submitting new assignments.

Great service. Always povide quick response and best online support and have very very less plagiarism.


Good writer that fulfil all the requirements that i have been told to the writer. The writer even called to discuss everything with me to continue my assighnment


Great work on time delivered for work, good understanding well prepared. References was well written in APA format

The writer had clear communication and ensured to give me a brief overview of how my assignment was going to be structured including an average of the words used in each section in order to avoid going over the limit. Didn't need to escalate even once because the quality of the work was in line with the Standard quality that I chose.

It was okay. Not bad, could do better! But marks were good, feedback was also good, so overall 4/5


The solution was excellent and all the requirements was taken into consideration.

On time and the assisgment is veryy well done. thank you very much. i'm happy and this is not the last time of me getting help


This is solid work thankyou for all the help with this PowerPoint; I m curious what grade ill get in it


Great Work Completed in under a Hour thank you so much. I got a 100 percent on my assignment.

I got 87%. Thanks for that. I am quite satisfied as You reviewed and changed when I ask for some changes.


I got a Distinction in this course. Highly satisfied with the expert work and effort.


I am very happy with this assignment. Thank you very much to the expert who has done this for me.


So far this is the highest marks I got for an assignment done by you guys. I got 42/50 for this assignment. The exact feedback from my lecturer was:
Introduction: Good introduction to assisted dying, especially in relation to laws within Australia. Introduction was a little too long.
Aim or Purpose: Good purpose but improved grammar needed. Good use of PICO.
Method: The method, while explained is very out of order. Try to write a methods section that can be followed in a step by step fashion

You did a good job just some details were missed enough attention. To be honest, you did much better job than the other websites. I would like to have more experience with you then I can give you more detailed feedback.


You cannot copy content of this page